Curriculum Vitae

September 17, 2007

E. Andrés Houseman, Sc.D.

Assistant Professor                                                               

Department of Work Environment                                         

University of Massachusetts, Lowell                                     

Tel:      978-934-3250

Fax:     978-452-5711

Email: andres_houseman@uml.edu

Education:

2003                Biostatistics                Sc.D.               Harvard School of Public Health

1990                Applied Mathematics   A.B.                 University of California at Berkeley

Academic Appointments:

2006-present   Assistant Professor                Work Environment      University of Massachusetts, Lowell

2006-present   Adjunct Assistant Professor   Biostatistics    Harvard School of Public Health

2003-2006       Research Scientist     Biostatistics    Harvard School of Public Health

1999-2003       Doctoral Candidate     Biostatistics    Harvard School of Public Health

Honors and Distinctions:

2000                Howard Hughes Medical Institute Predoctoral Fellowship

Business Experience:

2005-2006       Consultant, Battelle, Columbus, OH

1998-1999       Senior Professional Services Engineer, Actuate Software Corporation, San Mateo, CA

1994-1997       Senior Systems Analyst and Applications Developer, Horsely Bridge Partners, San Francisco, CA

1990-1994       Associate Scientist, Eisenberg, Olivieri, and Associates, Oakland, CA

Major Research Interest:

Latent variable models and their application to epidemiology (molecular and environmental)

Teaching Experience:

2006-2008       Instructor         University of Massachusetts Lowell Applied Regression 

Introduction to Mathematical Statistics

2004-2007       Instructor         Harvard School of Public Health         Introduction to Biostatistics

2005-2006       Instructor         Harvard School of Public Health         Applied Survival Analysis and Discrete Data Analysis

Publications:

1. Breton C. V., Zhou W., Kile M. L., Houseman E. A., Quamruzzaman Q., Rahman M., Mahiuddin G., Christiani D. C. (2007). Susceptibility to arsenic-induced skin lesions from polymorphisms in base excision repair genes. Carcinogenesis 28:1520-1525.

2. DeSantis S., Houseman E. A., Coull B., Betensky R. (2007). Penalized ordinal latent class models. Biostatistics (Epub ahead of print).

3. Dodson, R., Houseman E. A., Levy, J. I., Spengler, J. D., Shine, J. P., Bennett, D. H. (2007). Measured and Modeled Personal Exposures to and Risks from Volatile Organic Compounds. Environ. Sci. Technol. (in press).

4. Houseman E.A., Marsit C. J., Karagas M., Ryan L. M., (2007).  Penalized Item Response Theory models: application to epigenetic alterations in bladder cancer. Biometrics (Epub ahead of print).

5. Hsiung D. T., Marsit C. J., Houseman E. A., Eddy K., Furniss,C. S., McClean M. D., and Kelsey K. T.  (2007). Global DNA methylation level in whole blood is associated with head and neck squamous cell carcinoma.  Cancer Epidem. Biomar., 16:108-114.

6. Kile M. L., Houseman E. A., Breton C. V., Smith T., Quamruzzaman Q., Rahman M., Mahiuddin G., Christiani D. C. (2007). Dietary arsenic exposure in bangladesh. Environ Health Perspect 115:889-93.

7. Kile, M., Houseman E. A., Breton C. V., Quamruzzaman Q., Mahmuder R., Mahiuddin G., Christiani D. (2007).  Association between total ingested arsenic and toe nail arsenic concentrations.  J. Environ. Sci. Health, Part A, Vol. A42 (in press).

8. Loh M. M., Levy J. I., Spengler J. D., Houseman, E. A., Bennett D. H. (2007). Ranking Cancer Risks of Organic Hazardous Air Pollutants in the United States. Environ Health Perspect (in press).

9. Marsit C. J., Houseman E. A., Schned A. R., Karagas M. R., Kelsey K. T. (2007). Promoter hypermethylation is associated with current smoking, age, gender, and survival in bladder cancer. Carcinogenesis 28:1745-51.

10. McDevitt J. J. , Lai K. M., Rudnick S. N., Houseman E. A., First M. W., Milton D.K. (2007) Characterization of UVC Light Sensitivity of Vaccinia Virus. Appl Environ Microbiol. 73:5760-5766

11. Schmidt M, Houseman E.A., Ivanov A., Wolf D., (2007).  Comparative proteomic and transcriptomic profiling of the fission yeast Schizosaccharomyces pombe.  Mol. Sys. Biol., 3:79.

12. Breton C.V., Houseman E.A., Kile M.L., Quamruzzaman Q., Rahman M., Mahiuddin G., Christiani D.C., (2006).  Gender-specific protective effect of hemoglobin on arsenic-induced skin lesions. Cancer Epidem. Biomar., 15: 902-907.

13. Coull B. A., Houseman E. A., Betensky R. A., (2006).  A computationally tractable multivariate random effects model for clustered binary data. Biometrika, 93: 587-599.

14. Houseman E. A., Coull B. A., Betensky R. A. (2006).  Feature-specific constrained latent class analysis for genomic data. Biometrics, 62: 1062-1070.

15. Houseman E. A., Coull B. A., Ryan L. M., (2006). A functional-based distribution diagnostic for a linear model with correlated outcomes. Biometrika 93:911-926.

16. Houseman E. A., Coull B. A., Shine, J. P., (2006).  A nonstationary negative binomial time series with time-dependent covariates: Enterococcus counts in Boston Harbor.  J. Am. Stat. Assoc., 101:1365-1376.

17. Houseman E. A., Milton D. K. (2006).  Partial questionnaire designs, questionnaire nonresponse, and attributable fraction: applications to adult onset asthma.  Stat. Med., 25:1499-1519.

18. Loh M., Houseman E. A., Gray G. M., Spengler J. D., and Bennett D. H.  (2006) Measured Concentrations of VOC's in Non-residential Microenvironments.  Environ. Sci. Technol., 22: 6903- 6911.

19. Marsit C. J., Houseman E. A., Christensen B. C., Eddy K., Bueno R., Sugarbaker D. J., Nelson H. H., Karagas M. R. and Kelsey K. T.   Examination of a CpG Island Methylator Phenotype and Implications of Methylation Profiles in Solid Tumors. Cancer Res, 66: 10621-10629.

20. McCarty, K.M., Houseman, E.A., Quamruzzaman, Q., Rahman, M., Mahiuddin, G., Smith, T., Ryan, L., Christiani, D. (2006).   The impact of diet and betel nut use on skin lesions associated with drinking water arsenic in Pabna, Bangladesh.  Environ. Health Perspect.114: 334-340.

21. Sama, S.R., Milton, D.K., Hunt, P.R., Houseman, E.A., Henneberger, P.K., and Rosiello, R.A. (2006).  Case-by-case assessment of adult-onset asthma attributable to occupational exposures among members of a health maintenance organization. J. Occup. Environ. Med., 48:400-407.

22. Chen Y. C., Su H. J., Guo Y. L., Houseman E. A., Christiani D. C. (2005).   Interaction between environmental tobacco smoke and arsenic methylation ability on the risk of bladder cancer. Cancer Causes Control, 16: 75-81.

23. Houseman E. A. (2005).  A robust regression model for a first-order autoregressive time series with unequal spacing: application to water monitoring.  J. Roy. Stat. Soc. Series C-App., 54: 769-780.

24. Kile, M., Houseman E. A., Rodrigues E, Quamruzzaman Q., Mahmuder R., Mahiuddin G., Su L., Christiani D. (2005).  Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water.  Cancer Epidem. Biomar., 14: 2419-26.

25. Houseman E. A., Ryan L. M., Coull B. A. (2004).  Cholesky residuals for assessing normal errors in a linear model with correlated outcomes. J. Am. Stat. Assoc., 99: 383-394.

26. Houseman E. A., Ryan L. M., Levy J. I., Spengler J. D. (2002).  Autocorrelation in real-time continuous monitoring of microenvironments. J. Appl. Stat., 29: 855-872.

27. Levy J. I., Houseman E. A., Spengler J. D., Loh P., Ryan L. M. (2001).  Fine particulate matter and polycyclic aromatic hydrocarbon concentration Patterns in Roxbury, Massachusetts: A community-based GIS analysis.  Environ. Health Perspect., 109: 341-347.

28. Levy J. I., Houseman E. A., Ryan L. M., Richardson D., Spengler J. D. (2000).  Particle concentrations in urban microenvironments. Environ. Health Perspect., 108: 1051-1057.